United States Ophthalmic Market Trends

• Adoption of personalized medicine: The trend of personalized medicine is having a significant impact on the U.S. ophthalmic market. Personalized medicine takes into account individual variability in genes, environment, and lifestyle for each person. This allows doctors to better predict treatment responses, and tailor therapy and preventive care to each patient. When applied to ophthalmology, personalized medicine enables targeted treatment based on a patient's specific condition and biomarkers. Pharmaceutical companies are developing more precise drug therapies that focus on an individual's genetic profile or other health data. This paradigm shift will lead drug makers to concentrate on smaller patient segments that can benefit most from personalized treatments. For example, Novartis' anti-VEGF treatment Beovu is indicated for less frequent dosing in wet age-related macular degeneration patients identified as low-risk for retinal adverse events using Novartis's proprietary biomarker algorithm. This biomarker test helps minimize side effects by avoiding overtreatment in healthier patients. Data from the National Eye Institute also shows genetic factors play an important role in certain eye diseases such as age-related macular degeneration and glaucoma. With more insight into genetic contributions, drug companies can develop therapies targeted at patients with high-risk genetic profiles.

United States Ophthalmic Market Regional Insights:

• Northeast: The northeast region holds the leading position in the United States' ophthalmic market, boasting a market share of over 40%. The region is home to some of the largest and most affluent cities in the U.S., as well as a number of major pharmaceutical companies.
• West: The western region ranks as the second-largest ophthalmic market in the United States, holding a market share exceeding 30%. The region is home to a number of large and growing cities, as well as a number of biotech companies.
• South: The southern region ranks as the third-largest ophthalmic market in the United States, commanding a market share exceeding 15%. The region is home to a number of large and growing cities, as well as a number of pharmaceutical companies.
• Midwest: The Midwest region holds the position of the smallest ophthalmic market in the U.S., with a market share of less than 15%.
• The region is home to a number of large and growing cities, but it also has a number of rural areas.

Figure 1.  United States Ophthalmic Market Size (US$ Bn), 2023